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EN450

CAT: 0931-T77525-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T77525-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
793719-01-4
Target
Molecular Glues, NF-κB, E1/E2/E3 Enzyme
Related Pathways
PROTAC, NF-κB, Ubiquitination
Purity
0.9972
Bioactivity
EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.
Smiles
O=C(C=C)NC1=CC(=CC=C1Cl)S(=O)(=O)N(C)C
Molecular Formula
C11H13ClN2O3S
Molecular Weight
288.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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