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EN450

CAT: 0498-bs-82736C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82736C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1 (NFkB1) .1
Conjugation
Unconjugated
Buffer
White to off-white solid
Storage Conditions
-20°C

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