CKLF1-C19

• Target:

  CCR

• Related Pathways:

  GPCR/G Protein|||Microbiology/Virology|||Immunology/Inflammation

• Bioactivity:

  CKLF1-C19, the C-terminal peptide of human chemokine-like factor 1 (CKLF1), interacts with CCR4 and inhibits chemotaxis induced by CKLF1 and CCL17. It also suppresses allergic lung inflammation by inhibiting chemotaxis mediated by CCR3 and CCR4 [1].

• Smiles:

  CC (C) C[C@H] (NC (=O) [C@@H] (NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCC (O) =O) NC (=O) [C@H] (Cc1cnc[nH]1) NC (=O) [C@@H] (NC (=O) [C@@H]1CCCN1C (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@H] (Cc1ccc (O) cc1) NC (=O) [C@@H]1CCCN1C (=O) CNC (=O) [C@H] (CO) NC (=O) [C@@H]1CCCN1C (=O) [C@H] (CC (N) =O) NC (=O) [C@@H] (N) Cc1ccccc1) C (C) C) C (C) C) C (O) =O

• Molecular Formula:

  C103H161N27O28

• Molecular Weight:

  2225.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  960358-79-6