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Leptin (116-130)

CAT: 0931-T76221-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76221-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
189224-35-9
Target
IGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell death in amyloid toxicity models, showing promise for Alzheimer's disease (AD) research [1].
Smiles
C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CS)=O)CO)=O)CC(C)C)=O)CCC1)CCC(N)=O)=O)[C@@H](C)O)=O)CO)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCC(O)=O)=O)CCC2
Molecular Formula
C64H108N18O25S
Molecular Weight
1561.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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