Secalonic acid D

CAT: 0931-T75621-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T75621-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

35287-69-5

Target

C-Myc, Apoptosis, GSK-3, Others, Wnt/beta-catenin

Related Pathways

Others, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells, Cytoskeletal Signaling, Apoptosis

Bioactivity

Secalonic acid D, a toxic compound effective against tumor cells, is derived from the metabolites of Aspergillus aculeatus. It operates by activating GSK3-β and degrading β-catenin, consequently down-regulating c-Myc expression, arresting the cell cycle at the G1 phase, and inducing cell apoptosis [1] [2].

Smiles

C(OC)(=O)[C@]12C(C(=O)C=3C(O1)=CC=C(C3O)C=4C(O)=C5C(=CC4)O[C@]6(C(OC)=O)C(C5=O)=C(O)C[C@H](C)[C@H]6O)=C(O)C[C@H](C)[C@H]2O

Molecular Formula

C32H30O14

Molecular Weight

638.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19220226-01	Secalonic acid D
KCA68707-01	Secalonic acid F
HY-N15380	4,4′-Secalonic acid D
OR1071368-01	Acid-apeg6-acid
MBS6083807-01	Medronic Acid (Methylenebiphosphonic Acid, Methylenediphosphonic Acid, Methanebisphosphonic Acid, Methanediphosphonic Acid, MDP)
L2500-01	Lipoic Acid (Thioctic Acid, (±) -α-Lipoic Acid)
041005	Cacodylic Acid (dimethylarsonic acid, dimethylarsinic acid)
MBS641082-01	Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid)
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Secalonic acid D

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