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TD1092

CAT: 0931-T75010-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75010-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, PROTACs, Caspase, IAP
Related Pathways
Others, Apoptosis, Proteases/Proteasome, PROTAC
Bioactivity
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB pathway, diminishing the phosphorylation of IKK, IkBα, p65, and p38, and operates as a PROTAC. This compound is utilized in cancer research [1].
Molecular Formula
C55H70N8O9
Molecular Weight
987.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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