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JNJ-28583113

CAT: 0931-T74779-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T74779-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2765255-93-2
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9857
Bioactivity
JNJ-28583113 is a brain-penetrant TRPM2 antagonist that induces phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death. It inhibits microglia response to pro-inflammatory stimuli, used in the study of neurological diseases.
Smiles
O=C(OCC)CN1N=C(C=2C=CC(=CC2)C(F)(F)F)C3=C1CCCCC3
Molecular Formula
C19H21F3N2O2
Molecular Weight
366.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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