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DB1113

CAT: 0931-T74642-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74642-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2769753-53-7
Target
PROTACs, Ferroptosis, LIM Kinase, Autophagy, MAPK, Serine/threonin kinase, CDK, SIK, Bcr-Abl
Related Pathways
Autophagy, Angiogenesis, MAPK, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Metabolism, Apoptosis, PROTAC, Cytoskeletal Signaling
Bioactivity
DB1113 (Example 24) is a bifunctional compound designed for the targeted degradation of various kinases, including ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. This capability positions DB1113 as a valuable tool for research into diseases or disorders associated with aberrant kinase activity [1].
Smiles
C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCN1CCN(CC1)c1ccc(Nc2ncc3CN(C(=O)N(C)c3n2)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2C)cn1)C(C)(C)C)c1ccc(cc1)-c1scnc1C
Molecular Formula
C59H68F3N13O6S
Molecular Weight
1144.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA3424-1DB1113

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