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Trimipramine N-oxide

CAT: 0931-T74582-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T74582-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
14171-70-1
Target
Others, Drug Metabolite
Related Pathways
Metabolism, Others
Bioactivity
Trimipramine N-oxide, an active metabolite of the tricyclic antidepressant trimipramine, effectively inhibits human monoamine transporters for noradrenaline (hNAT), serotonin (hSERT), dopamine (hDAT), and the human organic cation transporters (hOCT1 and hOCT2), with IC50 values of 11.7, 3.59, 9.4, 9.35, and 27.4 nM, respectively. It is utilized in the research of depression and anxiety [1].
Smiles
CC(CN1c2ccccc2CCc2ccccc12)CN(C)(C)=O
Molecular Formula
C20H26N2O
Molecular Weight
310.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C