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Erythromycin A N-oxide

CAT: 0931-T37432Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T37432Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
992-65-4
Target
Others
Related Pathways
Others
Bioactivity
Erythromycin A N-oxide is a potential impurity found in commercial preparations of erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l) . Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin A N-oxide is also a precursor in the synthesis of clarithromycin .
Smiles
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)[N+](C)(C)[O-])[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C
Molecular Formula
C37H67NO14
Molecular Weight
749.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
E054-5MGErythromycin A N-oxide
CS-CM-00085Erythromycin-N-Oxide
CS-O-42846Erythromycin E N-oxide
TRC-E653408-25MGErythromycin A N-oxide (>80%)
RM-E182008-01Erythromycin EP Impurity H; Erythromycin A N-oxide (USP)
CS-O-42680Erythromycin EP Impurity E N-Oxide
CS-EO-04052Erythromycin EP Impurity F N-Oxide
CS-EO-04051Erythromycin EP Impurity D N-Oxide
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