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Rofapitide tetraxetan

CAT: 0931-T74546-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T74546-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2581741-18-4
Target
Immunology/Inflammation related, Others
Related Pathways
Immunology/Inflammation, Others
Purity
0.9546
Bioactivity
Rofapitide tetraxetan (FAP-2286) is a high-affinity, selective inhibitor of fibroblast activating protein (FAP) and a DOTA-pseudopeptide with an IC50 of 1.3–2.2 nM. FAP-2286 targets the tumour microenvironment and can be radiolabelled (e.g., with 68Ga) for use in positron emission tomography (PET) imaging.
Smiles
[H][C@@]12CCCN1C(=O)[C@]1([H])CCCN1C(=O)[C@H](CSCc1cc(CSCCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)cc(CSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@]([H])(NC2=O)[C@@H](C)O)C(O)=O)c1)NC(=O)CCCCC
Molecular Formula
C67H99N13O18S3
Molecular Weight
1470.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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