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Rofapitide tetraxetan

CAT: 0013-GTR19221147-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221147-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rofapitide tetraxetan (FAP-2286) is a potent and selective fibroblast activation protein (FAP) inhibitor with low nanomolar affinity. This DOTA-conjugated compound enables targeted imaging of the tumor stroma, as demonstrated by its use in preclinical and clinical PET imaging studies when radiolabeled with isotopes like 68Ga.
CAS Number
2581741-18-4
Field of Research
Immunology & Inflammation
Purity
95.46% (May vary between batches)
Solubility
DMSO:≥ 40 mg/mL; H2O:≥ 80 mg/mL
Smiles
[H][C@@]12CCCN1C (=O) [C@]1 ([H]) CCCN1C (=O) [C@H] (CSCc1cc (CSCCNC (=O) CN3CCN (CC (O) =O) CCN (CC (O) =O) CCN (CC (O) =O) CC3) cc (CSC[C@H] (NC (=O) [C@H] (Cc3ccccc3) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@@] ([H]) (NC2=O) [C@@H] (C) O) C (O) =O) c1) NC (=O) CCCCC
Molecular Formula
C67H99N13O18S3
Molecular Weight
1470.77
Storage Conditions
-20°C
Notes
For research use only.

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