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Imlunestrant tosylate

CAT: 0931-T74415-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74415-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408840-41-3
Target
Others, Estrogen Receptor/ERR
Related Pathways
Others, Endocrinology/Hormones
Bioactivity
Imlunestrant tosylate (LY-3484356) is a potent, orally active selective estrogen receptor degrader (SERD) with purely antagonistic properties, effectively inhibiting estrogen receptor (ER) -dependent gene transcription and cell growth. This compound is applicable in research on ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC) [1] [2].
Smiles
S(=O)(=O)(O)C1=CC=C(C)C=C1.OC1=CC=2C(=C3C(C=4C(O[C@@H]3C5=CC=C(OCCN6CC(CF)C6)C=C5)=CC(C(F)(F)F)=CC4)=CN2)C=C1
Molecular Formula
C36H32F4N2O6S
Molecular Weight
696.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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