PROTAC-O4I2

• Target :

  Apoptosis|||PROTACs

• Related Pathways :

  PROTAC|||Apoptosis

• Purity :

  0.9745

• Bioactivity :

  PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 ?M. PROTAC-O4I2 induced apoptosis in K562 WT cells.

• Smiles :

  O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCNC(=O)C=4N=C(NC5=CC=C(Cl)C=C5)SC4

• Molecular Formula :

  C29H29ClN6O5S

• Molecular Weight :

  609.1

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2785323-62-6