PROTAC-O4I2

• Target:

  Apoptosis|||PROTACs

• Related Pathways:

  PROTAC|||Apoptosis

• Purity:

  0.9745

• Bioactivity:

  PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 ?M. PROTAC-O4I2 induced apoptosis in K562 WT cells.

• Smiles:

  O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCNC(=O)C=4N=C(NC5=CC=C(Cl)C=C5)SC4

• Molecular Formula:

  C29H29ClN6O5S

• Molecular Weight:

  609.1

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2785323-62-6