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PROTAC-O4I2

CAT: 0931-T74186-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T74186-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2785323-62-6
Target
Apoptosis, PROTACs
Related Pathways
PROTAC, Apoptosis
Purity
0.9745
Bioactivity
PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCCNC(=O)C=4N=C(NC5=CC=C(Cl)C=C5)SC4
Molecular Formula
C29H29ClN6O5S
Molecular Weight
609.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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