Roxatidine

• Target :

  Others|||p38 MAPK|||Histamine Receptor|||NF-?B|||Caspase

• Related Pathways :

  NF-?B|||Others|||Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||MAPK|||GPCR/G Protein|||Neuroscience

• Bioactivity :

  Roxatidine, the active metabolite of Roxatidine acetate hydrochloride, serves as a histamine H2-receptor antagonist and exhibits anti-ulcer properties. It functions by suppressing the release of histamine, thereby inhibiting proton secretion, and also reduces the production of VEGF-1, a key indicator of inflammation and angiogenesis. This compound demonstrates an anti-allergic inflammatory effect [1].

• Smiles :

  C(C1=CC(OCCCNC(CO)=O)=CC=C1)N2CCCCC2

• Molecular Formula :

  C17H26N2O3

• Molecular Weight :

  306.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  78273-80-0