BQ-123 TFA

• Target:

  Others|||Endothelin Receptor

• Related Pathways:

  GPCR/G Protein|||Others

• Bioactivity:

  BQ-123 TFA, a potent and selective endothelin A (ETA) receptor antagonist, demonstrates an IC50 of 7.3 nM and a Ki of 25 nM. It effectively inhibits endothelin-1-induced proliferation of human pulmonary artery smooth muscle cells and reduces blood pressure in various rat hypertension models [1] [2] [3].

• Molecular Formula:

  C33H43F3N6O9

• Molecular Weight:

  724.72

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C