HTH-01-091 TFA

CAT: 0931-T73867-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T73867-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

CDK, RIP kinase, MELK, Pim, mTOR, DYRK, GSK-3, Others

Related Pathways

Others, NF-κB, Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

Bioactivity

HTH-01-091 TFA, a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), exhibits an IC50 of 10.5 nM. Besides its primary target, it also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2, positioning it as a promising agent for breast cancer research [1].

Molecular Formula

C28H29Cl2F3N4O4

Molecular Weight

613.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA3509-5	HTH-01-091
GTR19221583-01	HTH-01-091 TFA
HY-122665A	HTH-01-091 (TFA)
A8890-200	HTH-01-015
5622/50	HTH 01-015

HTH-01-091 TFA

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