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Antibiotic DC 81

CAT: 0931-T73678-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T73678-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
81307-24-6
Target
Apoptosis, Others, DNA/RNA Synthesis, Antibiotic
Related Pathways
Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology, Apoptosis
Bioactivity
Antibiotic DC 81, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotic produced by Streptomyces species, acts as a potent inhibitor of nucleic acid synthesis. It specifically recognizes and binds to certain DNA sequences, forming a labile covalent adduct [1] [2].
Smiles
[H][C@@]12CCCN1C(=O)c1cc(OC)c(O)cc1N=C2
Molecular Formula
C13H14N2O3
Molecular Weight
246.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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