Antibiotic DC 81

• Target:

  Apoptosis|||Others|||DNA/RNA Synthesis|||Antibiotic

• Related Pathways:

  Others|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology|||Apoptosis

• Bioactivity:

  Antibiotic DC 81, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotic produced by Streptomyces species, acts as a potent inhibitor of nucleic acid synthesis. It specifically recognizes and binds to certain DNA sequences, forming a labile covalent adduct [1] [2].

• Smiles:

  [H][C@@]12CCCN1C(=O)c1cc(OC)c(O)cc1N=C2

• Molecular Formula:

  C13H14N2O3

• Molecular Weight:

  246.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  81307-24-6