Products for Research Use Only

CPUL1

CAT: 0931-T73547-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73547-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2043660-80-4
Target
Others
Related Pathways
Others
Bioactivity
CPUL1, a TrxR inhibitor, exhibits proliferation-inhibitory and anti-metastatic effects on A549 cells by modulating epithelial-mesenchymal transition (EMT) through the induction of ROS-mediated ERK/JNK signaling, achieved by inhibiting TrxR1 enzyme activity. The efficacy of CPUL1 is enhanced when used in conjunction with α-Lipoic Acid or Dithiodipropionic acid [1].
Smiles
C(#N)C=1C(C2=C3C(N=C4C(=N3)C=CC=C4)=CC(N)=C2OC1N)C5=CC(Cl)=C(Cl)C=C5
Molecular Formula
C22H13Cl2N5O
Molecular Weight
434.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5815664CPUL1