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GK563

CAT: 0931-T73527-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T73527-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2351820-19-2
Target
Phospholipase, Apoptosis, Others
Related Pathways
Others, Metabolism, Apoptosis
Bioactivity
GK563, a selective Ca 2+-independent phospholipase A2 (GVIA iPLA2) inhibitor, exhibits a potent IC50 value of 1 nM and demonstrates 22,000-fold greater activity against GVIA iPLA2 compared to GIVA cPLA2. Its efficacy in reducing β-cell apoptosis triggered by proinflammatory cytokines suggests potential therapeutic benefits in combating autoimmune disorders, including type 1 diabetes.
Smiles
C(CC)[C@H]1[C@H](CCCCC2=CC=CC=C2)C(=O)O1
Molecular Formula
C16H22O2
Molecular Weight
246.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA3299-1GK563

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