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EVT801

CAT: 0931-T73516-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T73516-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1412453-70-3
Target
VEGFR, ERK
Related Pathways
Tyrosine Kinase/Adaptors, MAPK, Angiogenesis
Purity
0.974
Bioactivity
EVT801 is a highly selective and low-toxic VEGFR-3 inhibitor that inhibits VEGF-C-induced tumor lymphoid and angiogenesis and reduces important circulating immunosuppressive factors (CCL4, CCL5) and myeloid-derived suppressor cells (MDSC) .
Smiles
O=C1C(=C(N)N(CC)C=2C1=CC=C(C#C[C@@](COC)(C)O)N2)C=3NC=CN3
Molecular Formula
C19H21N5O3
Molecular Weight
367.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

(R)-2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-3-(1H-imidazol-2-yl)-1,8-naphthyridin-4(1H)-one
CAS Number1412453-70-3
PubChem CID71001861
IUPAC Name2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-3-(1H-imidazol-2-yl)-1,8-naphthyridin-4-one
Molecular FormulaC19H21N5O3
Molecular Weight367.4
XLogP0.3
Topological Polar Surface Area117
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count27
Formal Charge0
Complexity681
SMILES
CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C3=NC=CN3)N
InChI
InChI=1S/C19H21N5O3/c1-4-24-16(20)14(17-21-9-10-22-17)15(25)13-6-5-12(23-18(13)24)7-8-19(2,26)11-27-3/h5-6,9-10,26H,4,11,20H2,1-3H3,(H,21,22)/t19-/m1/s1
InChIKey
FQPLKTQWEHDNAB-LJQANCHMSA-N
Chemical Structure
2D Structure
2D structure of (R)-2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-3-(1H-imidazol-2-yl)-1,8-naphthyridin-4(1H)-one
CAS: 1412453-70-3
CID: 71001861
Formula: C19H21N5O3
MW: 367.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight367.4
XLogP30.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass367.16443955
Monoisotopic Mass367.16443955
Topological Polar Surface Area117 Ų
Heavy Atom Count27
Formal Charge0
Complexity681
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-152293-01EVT801
A24168-5EVT801 5mg
A24168-100EVT801 100mg
A24168-50EVT801 50mg
A24168-10EVT801 10mg

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