RegisterLogin

GSK761

CAT: 0931-T73497-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T73497-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Others|||Epigenetic Reader Domain
Related Pathways
Others|||Chromatin/Epigenetic
Bioactivity
GSK761, a selective inhibitor of speckled 140 kDa (SP140), exhibits an IC50 value of 77.79 nM. It impedes the differentiation of monocytes into inflammatory macrophages and attenuates lipopolysaccharide (LPS) -induced inflammatory activation. Furthermore, GSK761 promotes the generation of CD206+ regulatory macrophages through the inhibition of SP140.
Smiles
CC(C)(C)OCCC1=CC(=CC=C1)NC(=O)C2=CC=C(C=C2)C3=NC4=C(N3C)C=CC(=C4)C(=O)NC5=CC=CC(=C5)CCOC(C)(C)C
Molecular Formula
C40H46N4O4
Molecular Weight
646.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T27491-01GSK730
T68224-01GSK866
T69588-01GSK789
T70015-01GSK563
T70041-01GSK065
T27490-01GSK729
T6853-01GSK591
T24107-01GSK268
T15444-01GSK962
T6852-01GSK481

Alternative Products

CatalogName
MBS5815625GSK761
A24393-100GSK761 100mg
A24393-5GSK761 5mg
A24393-50GSK761 50mg
A24393-10GSK761 10mg

Popular Products