GSK321

• Target :

  Dehydrogenase|||Isocitrate Dehydrogenase (IDH)

• Related Pathways :

  Metabolism

• Purity :

  0.9973

• Bioactivity :

  GSK321 is a selective and potent mutant isocitrate dehydrogenase 1 (IDH1) inhibitor that inhibits lipid synthesis and blocks cell proliferation in OPA1-deficient MEFs and prevents cytoplasmic glutamine reductive carboxylation.GSK321 has been used in the study of leukemia.

• Smiles :

  C(N1C2=C(C(C(NC3=CC([C@H](C)O)=CC=C3)=O)=N1)CN(C(=O)C4=CC=CN4)C[C@H]2C)C5=CC=C(F)C=C5

• Molecular Formula :

  C28H28FN5O3

• Molecular Weight :

  501.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1816331-63-1