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MRS4719

CAT: 0931-T73453-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73453-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2840581-32-8
Target
Others, P2X Receptor
Related Pathways
Others, Membrane transporter/Ion channel, Neuroscience
Bioactivity
MRS4719, a potent P2X4 receptor antagonist, exhibits a half-maximal inhibitory concentration (IC50) of 0.503 μM for the human P2X4 receptor. Demonstrating both neuroprotective and neuro-rehabilitative effects, it can decrease infarct volume and brain atrophy in an ischemic stroke model. Additionally, MRS4719 mitigates ATP-induced calcium influx in primary human monocyte-derived macrophages, making it a valuable tool for researching ischemic stroke.
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O=C1NC=2C=3C=CC=CC3C=CC2N(C4=CC=NC(=C4)C5=NOC(=S)N5)C(=O)C1.N(CC)(CC)CC
Molecular Formula
C26H13N5O3S.C6H15N
Molecular Weight
504.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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