BI-2081

• Target:

  Others|||GPCR

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones|||Others

• Bioactivity:

  BI-2081, a GPR40 (FFAR1) partial agonist with an EC50 of 4 nM, promotes glucose-dependent insulin secretion and lowers plasma glucose levels. This compound is utilized in metabolic disease research, specifically targeting type 2 diabetes.

• Smiles:

  O([C@H]1C=2C(=C(C=CC2F)C3=C(C)C=C(OCCC(C)(C)O)C=C3C)CC1)C=4C=C5C(=CC4)[C@H](CC(O)=O)CO5

• Molecular Formula:

  C32H35FO6

• Molecular Weight:

  534.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1458656-71-7