SZM-1209

CAT: 0931-T73382-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T73382-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2919801-86-6

Target

MLK, Necroptosis, RIP kinase

Related Pathways

NF-κB, Apoptosis, MAPK

Bioactivity

SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM. It demonstrates substantial anti-necroptotic efficacy with an EC50 of 22.4 ± 8.1 nM and possesses therapeutic effects against systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI) [1].

Molecular Formula

C31H29F5N4O5S2

Molecular Weight

696.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19219604-01	SZM-1209
GTR19160406-01	NS 1209
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4021400/2	Stereo Microscope Model SZM-900 Trinocular
4021400/1	Stereo Microscope Model SZM-900 Binocular
S0B1114-01	GSK3β Recombinant Rabbit mAb (S-1209-170)
803685	PIC 1209-DIA 100-B7527 AC Signs
803689	PIC 1209-DIA 315-B7525 AC Signs
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SZM-1209

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