Products for Research Use Only
RegisterLogin

MSC-1186

CAT: 0931-T73378-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T73378-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2871698-23-4
Target
Serine/threonin kinase, Others
Related Pathways
Others, Metabolism, Cell Cycle/Checkpoint
Bioactivity
MSC-1186 is a potent and highly selective inhibitor targeting the pan-SRPK family, including SRPK1, SRPK2, and SRPK3, with IC 50 values of 2.7 nM, 81 nM, and 0.6 nM, respectively. Its specificity and effectiveness make it suitable for cancer research applications.
Smiles
N(CC1=C(N(S(C)(=O)=O)C)N=CC=C1)C2=NC(C=3NC=4C(N3)=CC=C(Cl)C4F)=NC=C2
Molecular Formula
C19H17ClFN7O2S
Molecular Weight
461.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-(3-(((2-(6-Chloro-7-fluoro-1H-benzo[d]imidazol-2-yl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)-N-methylmethanesulfonamide
CAS Number2871698-23-4
PubChem CID162368309
IUPAC NameN-[3-[[[2-(5-chloro-4-fluoro-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide
Molecular FormulaC19H17ClFN7O2S
Molecular Weight461.9
XLogP2.4
Topological Polar Surface Area125
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity714
SMILES
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2)C3=NC4=C(N3)C=CC(=C4F)Cl)S(=O)(=O)C
InChI
InChI=1S/C19H17ClFN7O2S/c1-28(31(2,29)30)19-11(4-3-8-23-19)10-24-14-7-9-22-17(26-14)18-25-13-6-5-12(20)15(21)16(13)27-18/h3-9H,10H2,1-2H3,(H,25,27)(H,22,24,26)
InChIKey
WBFJDKLBAAHKIL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(3-(((2-(6-Chloro-7-fluoro-1H-benzo[d]imidazol-2-yl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)-N-methylmethanesulfonamide
CAS: 2871698-23-4
CID: 162368309
Formula: C19H17ClFN7O2S
MW: 461.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight461.9
XLogP32.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass461.0836998
Monoisotopic Mass461.0836998
Topological Polar Surface Area125 Ų
Heavy Atom Count31
Formal Charge0
Complexity714
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T1950-01PND-1186
T63794-01PND-1186 hydrochloride
T200899-01MSC-5046
T37824-01MSC-4381
T201130-01MSC-1254
T33514-01MSC 2032964A
T60148-01MSC-4106
T77418-01MSC-1
T206646-01TO-1187
T68944-01NMI 1182

Alternative Products

CatalogName
BA4530-10MSC-1186
7927/50MSC 1186
462750-01PND-1186
FP103465-01PND 1186

Popular Products