MSC 2032964A

• Target :

  ASK|||p38 MAPK|||MAPK

• Related Pathways :

  MAPK|||Apoptosis

• Purity :

  >99.99%

• Bioactivity :

  MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.

• Smiles :

  FC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1

• Molecular Formula :

  C16H13F3N6O

• Molecular Weight :

  362.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1124381-43-6