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MSC 2032964A

CAT: 0931-T33514-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T33514-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1124381-43-6
Target
ASK, p38 MAPK, MAPK
Related Pathways
MAPK, Apoptosis
Purity
>99.99%
Bioactivity
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
Smiles
FC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
Molecular Formula
C16H13F3N6O
Molecular Weight
362.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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