Products for Research Use Only

RET-IN-20

CAT: 0931-T73309-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T73309-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, c-RET, Others
Related Pathways
Others, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
RET-IN-20, a potent RET inhibitor, demonstrates an IC50 value of 13.7 nM and effectively decreases the expression of p-Ret and p-Shc protein. Moreover, it induces apoptosis and exhibits antiproliferative and anti-tumor activity.
Smiles
CN1C=C(C(=N1)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)C(=O)N)F)C(=O)NC56CC7CC(C5)CC(C7)C6
Molecular Formula
C32H33FN6O4
Molecular Weight
584.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C