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OTS193320

CAT: 0931-T73225-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73225-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2093401-33-1
Target
Apoptosis, Histone Methyltransferase, Others
Related Pathways
Chromatin/Epigenetic, Others, Apoptosis
Bioactivity
OTS193320, an imidazopyridine compound, acts as an inhibitor of SUV39H2 methyltransferase activity. It effectively reduces global histone H3 lysine 9 tri-methylation levels in breast cancer cells, promoting apoptotic cell death. When combined with Doxorubicin (DOX), OTS193320 enhances the reduction of γ-H2AX levels and decreases cancer cell viability more significantly than when either agent is used alone.
Smiles
O(C)C1=C(C2=CN3C(=N2)C=C(N[C@@H]4CC[C@H](NCC5=CC=C(N(=O)=O)C=C5)CC4)C=C3)C=C(Cl)C(OC)=C1
Molecular Formula
C28H30ClN5O4
Molecular Weight
536.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-122182-01OTS193320

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