SMYD3-IN-2

• Target :

  Histone Methyltransferase|||Autophagy

• Related Pathways :

  Autophagy|||Chromatin/Epigenetic

• Bioactivity :

  SMYD3-IN-2, a potent inhibitor of SMYD3, demonstrates significant efficacy in combating gastric cancer by promoting lethal autophagy. It exhibits strong inhibitory activity against both SMYD3 and BGC823 cells, with IC 50 values of 0.81 ?M and 0.75 ?M, respectively. This compound holds potential for cancer research applications.

• Smiles :

  C1[C@@H]2[C@H]([C@]3(C4=CC=CC=C4NC3=O)O[C@@]2(C(=O)N1CC5=CC=CC=C5)O)C6=CC=C(C=C6)Br

• Molecular Formula :

  C26H21BrN2O4

• Molecular Weight :

  505.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C