Products for Research Use Only

EGFR-IN-74

CAT: 0931-T73170-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73170-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR, Others
Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM. It effectively induces apoptosis in cancer cells.
Smiles
CCOC(=O)C1=C(C2=C(C=CC(=C2)Br)N=C1N3C=CN=C3)N4CCN(CC4)C5=CC=CC=C5NS(=O)(=O)C6=CC=C(C=C6)C(F)(F)F
Molecular Formula
C32H28BrF3N6O4S
Molecular Weight
729.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C