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CDK7-IN-20

CAT: 0931-T73163-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73163-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, GSK-3, CDK
Related Pathways
Others, PI3K/Akt/mTOR signaling, Stem Cells, Cell Cycle/Checkpoint
Bioactivity
CDK7-IN-20 is a potent, selective, and irreversible inhibitor of Cyclin-Dependent Kinase 7 (CDK7) with an IC50 value of 4 nM, exhibiting over 206-fold selectivity against related kinases [CDK1, CDK2, CDK3, CDK5, CDK6, CDK9, and CDK12]. It holds potential for research into autosomal dominant polycystic kidney disease (ADPKD) .
Smiles
C=CC(=O)NC1=CC=C(C=C1)C(=O)NC2=NNC3=C2C=C(C=C3)C4=CC(=CN=C4)NC[C@H](C5=CC=CC=C5)O
Molecular Formula
C30H26N6O3
Molecular Weight
518.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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