CDK7-IN-20

• Target :

  Others|||GSK-3|||CDK

• Related Pathways :

  Others|||PI3K/Akt/mTOR signaling|||Stem Cells|||Cell Cycle/Checkpoint

• Bioactivity :

  CDK7-IN-20 is a potent, selective, and irreversible inhibitor of Cyclin-Dependent Kinase 7 (CDK7) with an IC50 value of 4 nM, exhibiting over 206-fold selectivity against related kinases [CDK1, CDK2, CDK3, CDK5, CDK6, CDK9, and CDK12]. It holds potential for research into autosomal dominant polycystic kidney disease (ADPKD) .

• Smiles :

  C=CC(=O)NC1=CC=C(C=C1)C(=O)NC2=NNC3=C2C=C(C=C3)C4=CC(=CN=C4)NC[C@H](C5=CC=CC=C5)O

• Molecular Formula :

  C30H26N6O3

• Molecular Weight :

  518.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C