EGFR-IN-61

CAT: 0931-T73128-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T73128-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2890261-81-9

Target

EGFR

Related Pathways

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Bioactivity

EGFR-IN-61 (compound 22a), a potent EGFR kinase inhibitor, exhibits IC50 values of 42 nM for L858R/T790M, 137 nM for L858R/T790M/C797S, and 743 nM for WT. Additionally, it demonstrates antiproliferative activity against the A549 and H1975 cell lines, with IC50 values of 2.14 μM and 1.82 μM, respectively [1].

Smiles

CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C2=CC(=NC=C2)Cl)NC3=NC=CC(=N3)C4=CN(C5=CC=CC=C54)CCCO)OC

Molecular Formula

C33H37ClN8O3

Molecular Weight

629.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T30185-01	AT 61
T89580-01	RNB-61
T86651-01	HSD17B13-IN-61
T210888-01	HDAC6-IN-61
T79541-01	HDAC-IN-61
T69545	Mpro 61
T204999-01	RNB 61
T200932-01	HLCL-61
T27559-01	HT-61
T3070-01	GANT 61

Alternative Products

Catalog	Name
HY-147860	EGFR-IN-61
HY-114956	AT-61
MBS5779821	AT 61
B7806-25	HLCL-61
BA3015-1	ARD-61
112214	Mpro 61
526868	HT-61
HY-163258	HSD17B13-IN-61
3191/10	GANT 61
GTR18027058	61 Antibody

EGFR-IN-61

Related Products

Alternative Products

Popular Products