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TRK/ALK-IN-1

CAT: 0931-T72931-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72931-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ALK, Others, Trk receptor
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors
Bioactivity
TRK/ALK-IN-1 is a potent dual inhibitor of TRK and ALK, exhibiting good correlation between its enzymatic inhibition and anti-proliferative activities, with IC50 values of 2.2 nM for TRKA, 9.3 nM for ALK WT, and 38 nM for ALK L1196M. It holds potential for cancer research applications.
Smiles
CN1CCN(CC1)C2=C(C=C(C=C2)NC(=O)[C@@H]3CCCN3C4=NC(=NC=C4Cl)NC5=CC(=CC(=C5)F)F)C(=O)N6CCSCC6
Molecular Formula
C31H35ClF2N8O2S
Molecular Weight
657.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-144732TRK/ALK-IN-1
HY-12327Trk-IN-1
HY-151945TRK II-IN-1
JCD24619-01DDR-TRK-1
A1367-10ALK-IN-1
305597-01ALK-1
338192-01Trk A
PA1321-STrk-A

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