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(+) -Norfenfluramine

CAT: 0931-T72510-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72510-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
19036-73-8
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
(+) -Norfenfluramine, the principal hepatic metabolite of (+) -fenfluramine, acts as a selective agonist for the 5-HT2B receptor, exhibiting a potent K i of 11.2 nM. It significantly promotes the hydrolysis of inositol phosphates and heightens intracellular Ca2+ levels. This compound is valuable in the study of primary pulmonary hypertension and valvular heart disease.
Smiles
C[C@H](N)Cc1cccc(c1)C(F)(F)F
Molecular Formula
C10H12F3N
Molecular Weight
203.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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