EFdA-TP tetrasodium

• Target:

  DNA/RNA Synthesis|||HIV Protease|||Reverse Transcriptase

• Related Pathways:

  DNA Damage/DNA Repair|||Microbiology/Virology|||Cell Cycle/Checkpoint|||Proteases/Proteasome

• Bioactivity:

  EFdA-TP tetrasodium, a potent nucleoside reverse transcriptase (RT) inhibitor, effectively halts RT-catalyzed DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT) . It employs multiple mechanisms to inhibit HIV-1 RT [1].

• Smiles:

  C#C[C@@]1(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)[C@@H](O)C[C@H](N2C=NC3=C(N)N=C(F)N=C32)O1.[Na+].[Na+].[Na+].[Na+]

• Molecular Formula:

  C12H11FN5Na4O12P3

• Molecular Weight:

  621.12

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2883783-00-2