Infigratinib acetate

CAT: 0931-T71002-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T71002-01Size:25 mg
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AVAILABILITY: InStock
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CAS Number
1310746-17-8
Target
Others
Related Pathways
Others
Bioactivity
Infigratinib acetate, also known as, BGJ398 acetate or NVP-BGJ398 acetate, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. pan FGFR kinase inhibitor BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Infigratinib acetate was approved in 2021 to treat adults with cholangiocarcinoma whose disease meets certain criteria.
Smiles
CC(O)=O.CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1
Molecular Formula
C28H35Cl2N7O5
Molecular Weight
620.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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