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Benastatin B

CAT: 0931-T70798-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T70798-01Size:25 mg
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CAS Number
138968-86-2
Target
Others|||GST|||Antibacterial
Related Pathways
Oxidation-Reduction|||Others|||Microbiology/Virology
Bioactivity
Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme) .2 Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively) .3 It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml) .
Smiles
OC1=C2C=3C(=C(O)C4=C(C3)C(C)(C)C=5C(C4=O)=C(O)C=C(O)C5)CCC2=CC(CCCCC)=C1C(O)=O
Molecular Formula
C30H30O7
Molecular Weight
502.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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