Benastatin B

• Target :

  Others|||GST|||Antibacterial

• Related Pathways :

  Oxidation-Reduction|||Others|||Microbiology/Virology

• Bioactivity :

  Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme) .2 Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively) .3 It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml) .

• Smiles :

  OC1=C2C=3C(=C(O)C4=C(C3)C(C)(C)C=5C(C4=O)=C(O)C=C(O)C5)CCC2=CC(CCCCC)=C1C(O)=O

• Molecular Formula :

  C30H30O7

• Molecular Weight :

  502.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  138968-86-2