Benastatin A

• Target:

  Others|||GST

• Related Pathways:

  Oxidation-Reduction|||Others

• Bioactivity:

  Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 ?M for the rat liver enzyme) .2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus (MRSA; MIC = 3.12 ?g/ml) . It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 ?M, respectively.3

• Smiles:

  CCCCCc1cc2ccc3c (O) c4C (=O) c5c (O) cc (O) cc5C (C) (C) c4cc3c2c (O) c1C (O) =O

• Molecular Formula:

  C30H28O7

• Molecular Weight:

  500.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  138968-85-1