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Benastatin A

CAT: 0931-T35978Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T35978Size:2 mg
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CAS Number
138968-85-1
Target
Others|||GST
Related Pathways
Oxidation-Reduction|||Others
Bioactivity
Benastatin A is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2,3It inhibits glutathione S-transferase (GST; Ki= 5 ?M for the rat liver enzyme) .2Benastatin A is active against several bacteria, including methicillin-resistantS. aureus (MRSA; MIC = 3.12 ?g/ml) . It induces apoptosis and cell cycle arrest at the G1/G0phase in Colon 26 mouse colon cancer cells when used at concentrations of 20 and 16 ?M, respectively.3
Smiles
CCCCCc1cc2ccc3c(O)c4C(=O)c5c(O)cc(O)cc5C(C)(C)c4cc3c2c(O)c1C(O)=O
Molecular Formula
C30H28O7
Molecular Weight
500.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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