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ML252

CAT: 0931-T70786-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T70786-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1392494-64-2
Target
Others, Potassium Channel, Cytochromes P450
Related Pathways
Membrane transporter/Ion channel, Others, Metabolism
Bioactivity
ML252 is a selective potassium channel inhibitor, specifically targeting the KCNQ2 channel (Kv7.2) with an IC50 value of 69 nM. Additionally, ML252 demonstrates inhibitory activity against Cytochrome P450 isoforms, including IC50 values of 6.1 nM (CYP1A2), 18.9 nM (CYP2C9), 3.9 nM (CYP3A4), and 19.9 nM (CYP2D6) .
Smiles
N(C([C@@H](CC)C1=CC=CC=C1)=O)C2=C(C=CC=C2)N3CCCC3
Molecular Formula
C20H24N2O
Molecular Weight
308.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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