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DFL23448

CAT: 0931-T70632-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T70632-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1445753-16-1
Target
Others
Related Pathways
Others
Bioactivity
DFL23448 is a TRPM8-selective ion channel antagonist, modifying bladder function and reduces bladder overactivity in awake rats.
Smiles
OC1=C(SC(=N1)C2=CC(F)=CC=C2)C3=NN(CC)N=N3
Molecular Formula
C12H10FN5OS
Molecular Weight
291.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

5-(2-ethyl-2H-tetrazol-5-yl)-2-(3-fluorophenyl)-1,3-thiazol-4-ol

a TRPM8 channel antagonist; structure in first source

CAS Number1445753-16-1
PubChem CID136218657
IUPAC Name5-(2-ethyltetrazol-5-yl)-2-(3-fluorophenyl)-1,3-thiazol-4-ol
Molecular FormulaC12H10FN5OS
Molecular Weight291.31
XLogP2.9
Topological Polar Surface Area105
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity339
SMILES
CCN1N=C(N=N1)C2=C(N=C(S2)C3=CC(=CC=C3)F)O
InChI
InChI=1S/C12H10FN5OS/c1-2-18-16-10(15-17-18)9-11(19)14-12(20-9)7-4-3-5-8(13)6-7/h3-6,19H,2H2,1H3
InChIKey
HOVUYEIYKRUBIF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-(2-ethyl-2H-tetrazol-5-yl)-2-(3-fluorophenyl)-1,3-thiazol-4-ol
CAS: 1445753-16-1
CID: 136218657
Formula: C12H10FN5OS
MW: 291.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight291.31
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass291.05900930
Monoisotopic Mass291.05900930
Topological Polar Surface Area105 Ų
Heavy Atom Count20
Formal Charge0
Complexity339
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-117372DFL23448

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