Products for Research Use Only
RegisterLogin

Pamiparib hydrate

CAT: 0931-T70115-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T70115-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1858211-28-5
Target
Others
Related Pathways
Others
Bioactivity
Pamiparib, also known as BGB-290, is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis. BGB-290 may both potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.
Smiles
O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
Molecular Formula
C16H21FN4O4
Molecular Weight
352.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T5058-01Pamiparib
T28293-01Pamiparib maleate
T35414-01α-Cyclodextrin (hydrate)
T0910-01Terpin hydrate
T28485-01Quinaprilat hydrate
T209778-01Pyranine hydrate
TN10371-01Citrinin hydrate
T88555-01Naringin hydrate
TN2021Osthol hydrate
T26054Regadenoson hydrate

Alternative Products

CatalogName
MBS5812658Pamiparib hydrate
BA4359-50Pamiparib

Popular Products