Pamiparib

• Target :

  PARP

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity :

  0.9969

• Bioactivity :

  Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor with IC50 values of 0.9 nM for PARP1 and 0.5 nM for PARP2. It exhibits strong PARP trapping, has the capability to penetrate the brain, and is used for researching various cancers, including solid tumors.

• Smiles :

  C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34

• Molecular Formula :

  C16H15FN4O

• Molecular Weight :

  298.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1446261-44-4