Cilofexor tromethamine

• Target :

  FXR|||Autophagy|||Others

• Related Pathways :

  Metabolism|||Autophagy|||Others

• Bioactivity :

  Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.

• Smiles :

  NC(CO)(CO)CO.OC(=O)c1ccnc(c1)N1CC(O)(C1)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1Cl

• Molecular Formula :

  C32H33Cl3N4O8

• Molecular Weight :

  707.99

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2253764-93-9