Cilofexor tromethamine

CAT: 0931-MF-0144277-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0144277-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2253764-93-9
Target
FXR|||Autophagy|||Others
Related Pathways
Metabolism|||Autophagy|||Others
Bioactivity
Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.
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NC(CO)(CO)CO.OC(=O)c1ccnc(c1)N1CC(O)(C1)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1Cl
Molecular Formula
C32H33Cl3N4O8
Molecular Weight
707.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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