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Clesacostat tromethamine

CAT: 0931-T202745-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T202745-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2334472-62-5
Bioactivity
Clesacostat (PF-05221304) is a potent and selective ACC inhibitor, with hACC1 IC50 of 13 nM and hACC2 IC50 of 9 nM. In animal models, PF-05221304 specifically inhibits hepatic DNL and demonstrates a significant safety margin for thrombocytopenia in non-human primate models.
Smiles
O=C(O)C=1C=CC(=CC1)C2=NC(OC)=CC(=C2)C(=O)N3CCC4(CC(=O)C5=C(C=NN5C(C)C)C4)CC3.OCC(N)(CO)CO
Molecular Formula
C32H41N5O8
Molecular Weight
623.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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