TC-5115

CAT: 0931-T69624-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T69624-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2458182-10-8
Target
Others
Related Pathways
Others
Bioactivity
TC-5115 is a potent inhibitor of MLL methyltransferase with IC50 value of 16 nM. TC-5115 may lead to the development of a new therapy for the treatment of human MLL leukemia. The mixed-lineage leukemia (MLL) protein, also known as MLL1, is a lysine methyltransferase specifically responsible for methylation of histone 3 lysine 4. MLL has been pursued as an attractive therapeutic target for the treatment of acute leukemia carrying the MLL fusion gene or MLL leukemia.
Smiles
O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CN(CC4CN(CC5=CC=CS5)C4)CC[C@@H](C(O)=O)N)[C@H]1O
Molecular Formula
C23H32N8O5S
Molecular Weight
532.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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