Leupeptin HCl

CAT: 0931-T69297-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T69297-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
39740-82-4
Target
Others
Related Pathways
Others
Bioactivity
Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C) . It does not inhibit ?-chymotrypsin or thrombin. Leupeptin is a competitive transition state inhibitor and its inhibition may be relieved by an excess of substrate.
Smiles
[C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)(C(N[C@@H](CCCNC(=N)N)C=O)=O)CC(C)C.Cl
Molecular Formula
C20H39ClN6O4
Molecular Weight
463.01
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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