Leupeptin

• Target:

  Virus Protease|||Cysteine Protease|||Serine Protease

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome

• Bioactivity:

  Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C) . Leupeptin does not inhibit ?-chymotrypsin or thrombin.

• Smiles:

  CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)NC(CCCNC(N)=N)C=O

• Molecular Formula:

  C20H38N6O4

• Molecular Weight:

  426.562

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  24365-47-7