Fenobam hydrate

• Target:

  Apoptosis|||Others|||GluR

• Related Pathways:

  Neuroscience|||Others|||Apoptosis

• Bioactivity:

  Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5) . It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits basal activity of mGluR5. Fenobam reduces stress-induced hyperthermia, exhibits anxiolytic-like activity, and may induce analgesia.

• Smiles:

  O.CN1CC (=O) N=C1NC (=O) Nc1cccc (Cl) c1

• Molecular Formula:

  C11H13ClN4O3

• Molecular Weight:

  284.7

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  63540-28-3